This is from a premillennial perspective:
However, Daniel 2:4 begins a section written in Aramaic-a Gentile language-that describes the actions of God through history as Gentile kingdoms are allowed to trample under-foot the nation of Israel. The main characters are now pagan Gentiles.
It is appropriate that the Gentile section begins with a panoramic overview of Gentile history from that point forward to the last times. Nebuchadnezzar’s dream of the statue foretells a succession of Gentile empires. The period starts with a relatively noble king and empire-the gold head personified by King Nebuchadnezzar. Then the empires deteriorate all the way to being poorly mixed with clay. Babylon, Medo-Persia, Greece, and Rome. The Roman dominion lasts until the Kingdom of God replaces and destroys all the kingdoms of men and extends its rule over all Creation. However, the Roman dominion goes through a dramatic transition: the first phase is as a solid, iron, unified empire; the second is as a divided, weakened entity mixed with other peoples. However, all of these centuries foreseen here are dominated by Gentile, not Jewish, rule-right up until the Kingdom of God. This whole period, then, is what Jesus referred to in Luke 21:24 as, “the times of the gentiles”. It is during this long era of history characterized by Gentile dominance that Jerusalem, according to Jesus’ prediction, would be trampled under foot by the Gentiles. At the end of this era Jerusalem would logically be freed from Gentile rule and alternatively be under Jewish rule. So there is a “sign of the times” to be learned here: the end of the Times of the Gentiles will coincide with the rise of the Jewish nation; the rise of the Jewish nation would accompany the decline of the last of the Gentile empires (the 10 kingdoms of Western Europe) and shortly precede the coming of the everlasting Kingdom of God.